Opportunity Information: Apply for PAR 19 163

This grant opportunity, titled "Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R21-Clinical Trial Not Allowed)" (Funding Opportunity Number PAR 19 163), is a National Institutes of Health (NIH) discretionary grant program designed to speed up new discoveries about adolescent health and development by using data that already exist. Instead of funding new data collection, the program encourages researchers to analyze the publicly available ABCD Study dataset, which is shared through the NIMH Data Archive. The intent is to get more scientific value out of one of the largest long-term studies of youth development by supporting creative, focused research projects that can generate insights relatively quickly.

The ABCD Study follows children beginning at ages 9 to 10 and collects repeated measures over a 10-year period. The dataset is broad and multidisciplinary, covering physical health and mental health, cognitive function and learning, substance use behaviors and risk factors, cultural and environmental influences, and detailed information on brain structure and function. Because the study is longitudinal, it allows researchers to examine how early-life experiences and exposures relate to later outcomes, how developmental trajectories change over time, and how brain and behavior develop together during the transition from late childhood into adolescence and beyond.

The core purpose of the FOA is to increase knowledge of adolescent health and development by funding secondary analyses of the ABCD public-use data. Projects funded under this announcement would generally be expected to use rigorous analytic approaches to answer specific research questions, test hypotheses, explore mechanisms, or identify patterns and predictors across the rich ABCD measures. Since this is an R21 mechanism, the emphasis typically aligns with exploratory or developmental research that is innovative and can open new directions, rather than large, multi-year definitive trials. The "Clinical Trial Not Allowed" designation makes clear that the funded work should not involve conducting a clinical trial; the focus is on analyzing existing data rather than enrolling participants or testing an intervention prospectively.

Eligibility is broad and includes many types of domestic institutions and organizations, reflecting an effort to draw participation from across the research and public health ecosystem. Eligible applicants listed include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, non-U.S. entities (foreign organizations), Indian/Native American tribal governments other than federally recognized, and U.S. territories or possessions. In practice, this wide eligibility is meant to encourage diverse perspectives, methods, and institutional participation in analyzing the ABCD data.

From a funding details standpoint, the program is offered as a grant under NIH, with an award ceiling listed at $200,000. The CFDA numbers associated with the opportunity are 93.242, 93.279, 93.307, 93.313, 93.399, 93.853, and 93.865, reflecting multiple NIH program areas that can be connected to child health, mental health, substance use, neuroscience, and related domains. The opportunity was created on 2019-01-09, and the original closing date shown is 2022-01-07. The administering agency is NIH.

Overall, this FOA is essentially an invitation to researchers to take advantage of the ABCD Study's scale, depth, and repeated measurements to answer timely questions about how adolescents develop and what factors shape health, mental health, cognition, behavior, and brain development. It prioritizes maximizing the impact of an existing national research resource by funding well-scoped analytic projects that can generate new findings without the time and cost of launching a new cohort study. For more background on the underlying dataset and study design, the announcement points applicants to the ABCD Study website at www.abcdstudy.org.

  • The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R21-Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242, 93.279, 93.307, 93.313, 93.399, 93.853, 93.865.
  • This funding opportunity was created on 2019-01-09.
  • Applicants must submit their applications by 2022-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 19 163

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