Opportunity Information: Apply for PAR 19 114

The NIH funding opportunity PAR-19-114, titled "Non-human Primates Facilities to Support HIV/AIDS-related Research (C06 Clinical Trial Not Allowed)," supports one main purpose: providing grant funding to modernize existing research facilities that are directly involved in HIV/AIDS-related research and that support non-human primate (NHP) colonies. The focus is on upgrading physical infrastructure, especially animal housing and research-dedicated space, so that institutions can better support NIH-funded scientists whose work depends on these animals and the specialized environments required for ethically and safely conducting animal-based HIV/AIDS research.

This is a discretionary grant program under the NIH (CFDA 93.352) using the C06 activity mechanism, which is typically associated with construction and facility improvement. The FOA is not meant to pay for routine operations. Projects limited to general maintenance, basic repairs, or standard upkeep are explicitly described as not appropriate. Instead, the intent is to fund modernization efforts that materially improve capability, compliance, and research readiness, such as renovating or reconfiguring animal housing infrastructure, updating systems that enable appropriate animal care and biosafety, and improving dedicated research space tied to animal-based HIV/AIDS investigations.

A central requirement is that the proposed facility improvements must be justified by demonstrated need tied to NIH-funded investigators. In practical terms, an application needs to show that there is an active base of NIH-supported research that uses the space and/or depends on the animals produced and cared for by the facility. The facility improvements should therefore be positioned as enabling or strengthening ongoing NIH-funded HIV/AIDS-related work, rather than building capacity in the abstract. The FOA specifically encourages applications from institutions that maintain or support NHP colonies, recognizing that the housing environment and adjacent research areas are critical bottlenecks for animal-related research programs.

Eligibility is limited to U.S.-based organizations, including public and state-controlled institutions of higher education, private institutions of higher education, and other qualifying domestic entities. The FOA highlights that a range of institutions may apply, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). Foreign participation is not allowed: non-U.S. entities are ineligible, non-U.S. components of U.S. organizations are ineligible, and foreign components (as defined by NIH policy) are not permitted under this announcement.

Administratively, the opportunity was created on 2018-12-18 and listed an original closing date of 2019-03-06. The announcement indicates that clinical trials are not allowed, which aligns with the facility-focused nature of the program: the funding is intended to improve physical research infrastructure supporting HIV/AIDS-related animal research rather than to run clinical trial activities.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Non-human Primates Facilities to Support HIV/AIDS-related Research (C06 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.352.
  • This funding opportunity was created on 2018-12-18.
  • Applicants must submit their applications by 2019-03-06. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others.
Apply for PAR 19 114

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FAQs: NIH PAR-19-114 - Non-human Primates Facilities to Support HIV/AIDS-related Research (C06 Clinical Trial Not Allowed)

What is the main purpose of PAR-19-114?

The main purpose is to provide NIH grant funding to modernize existing research facilities that directly support HIV/AIDS-related research involving non-human primates (NHPs). The emphasis is on upgrading physical infrastructure such as animal housing and research-dedicated space so institutions can better support NIH-funded scientists who rely on NHP colonies and specialized research environments.

What type of grant mechanism is used for this opportunity?

This opportunity uses the NIH C06 activity mechanism, which is typically associated with construction and facility improvement projects rather than research operations.

Which NIH program classification and CFDA number are associated with this FOA?

It is a discretionary grant program under the NIH with CFDA number 93.352.

What kinds of projects are considered a good fit for this funding?

Projects that modernize or materially improve facilities used for HIV/AIDS-related research involving NHPs. Examples described in the opportunity include renovating or reconfiguring animal housing infrastructure, updating facility systems needed for appropriate animal care and biosafety, and improving dedicated research space tied to animal-based HIV/AIDS investigations.

Is the funding intended to cover routine operations or day-to-day animal facility costs?

No. The FOA states it is not meant to pay for routine operations.

Are general maintenance or basic repair projects eligible under this FOA?

No. Projects limited to general maintenance, basic repairs, or standard upkeep are explicitly described as not appropriate for this funding opportunity.

What is meant by "modernization" in the context of this FOA?

Modernization refers to facility improvements that go beyond upkeep and that materially improve capability, compliance, and research readiness. The FOA highlights upgrades to animal housing and related infrastructure, systems supporting animal care and biosafety, and research-dedicated space that supports HIV/AIDS-related animal research.

Does the FOA require a connection to NIH-funded investigators?

Yes. A central requirement is that proposed improvements must be justified by demonstrated need tied to NIH-funded investigators. Applications are expected to show an active base of NIH-supported research that uses the space and/or depends on the animals produced and cared for by the facility.

Can an applicant propose improvements to build general capacity without linking them to current NIH-funded HIV/AIDS work?

The FOA emphasizes that improvements should enable or strengthen ongoing NIH-funded HIV/AIDS-related research, rather than building capacity in the abstract. Applicants should position the facility upgrades as directly supporting NIH-funded investigators and their HIV/AIDS-related animal research needs.

What facilities are specifically encouraged to apply?

The FOA specifically encourages applications from institutions that maintain or support NHP colonies, recognizing that animal housing environments and adjacent research areas can be critical bottlenecks for animal-related HIV/AIDS research programs.

Who is eligible to apply?

Eligibility is limited to U.S.-based organizations, including public and state-controlled institutions of higher education, private institutions of higher education, and other qualifying domestic entities.

Does the FOA mention specific categories of U.S. institutions that may apply?

Yes. The FOA highlights that a range of institutions may apply, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), among other qualifying domestic entities.

Are foreign organizations eligible to apply?

No. Foreign participation is not allowed. Non-U.S. entities are ineligible.

Can a U.S. organization include a non-U.S. component in the application?

No. The FOA states that non-U.S. components of U.S. organizations are ineligible under this announcement.

Are foreign components allowed under NIH policy for this opportunity?

No. Foreign components (as defined by NIH policy) are not permitted under this announcement.

Are clinical trials allowed under PAR-19-114?

No. The announcement states "Clinical Trial Not Allowed," consistent with the facility improvement focus of the program.

Why does the FOA specify that clinical trials are not allowed?

The funding is intended to improve physical research infrastructure that supports HIV/AIDS-related animal research using NHPs, rather than to support clinical trial activities.

When was this funding opportunity created?

The opportunity was created on 2018-12-18.

What was the original closing date listed for this opportunity?

The original closing date listed is 2019-03-06.

What is the core focus of the facility upgrades supported by this FOA?

Upgrading physical infrastructure, especially animal housing and research-dedicated space, to better support ethically and safely conducted HIV/AIDS-related research that depends on NHP colonies and specialized environments.

How should applicants describe the benefit of the proposed improvements?

Based on the FOA description, applicants should frame improvements as directly supporting NIH-funded investigators and enabling or strengthening ongoing NIH-funded HIV/AIDS-related research that relies on the facility space and/or NHPs produced and cared for by the facility.

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