Opportunity Information: Apply for RFA DE 19 003
This funding opportunity (RFA-DE-19-003) is a limited competition renewal for the FaceBase 3 Data Management and Integration Hub, a central resource supported by the National Institute of Dental and Craniofacial Research (NIDCR) within NIH. FaceBase (www.facebase.org) functions as a data repository and knowledgebase designed to speed progress in craniofacial research by assembling, organizing, and sharing high-value datasets and related tools focused on craniofacial development and craniofacial dysmorphologies. The Hub is essentially the backbone of the FaceBase program, making sure that data produced across the program can be curated properly, connected to other relevant datasets, and delivered to researchers in a way that is searchable, usable, and scientifically meaningful.
The core purpose of the award is to continue and expand the Hub responsibilities that have existed since FaceBase began. That includes collecting datasets and analytic tools produced by FaceBase dataset-generating "spoke" projects, performing curation and quality control, integrating those resources into coherent data structures, and disseminating them broadly through the FaceBase website. In practical terms, the Hub is expected to maintain and improve the repository infrastructure, ensure consistent metadata and standards so datasets can be compared and combined, and provide user-facing functionality that helps researchers find what they need and understand how to use it. A major emphasis is placed on integration and presentation of existing FaceBase datasets, along with ongoing development or adoption of improved approaches for data search, browsing, and visualization so the platform remains modern and useful as data types and community needs evolve.
FaceBase 3 also adds an important new mission beyond simply managing datasets generated by FaceBase spokes. The Hub is expected to actively work with investigators across the broader craniofacial research community to bring external datasets into FaceBase. That means helping researchers make their data compatible with FaceBase data models, guiding them on formatting and metadata expectations, and then curating and integrating those new datasets alongside existing FaceBase holdings. This expansion is meant to increase the reach and impact of FaceBase by turning it into a more comprehensive community repository, not just a home for data created within the immediate FaceBase program. The goal is to improve interoperability and reuse, so that studies from different labs, methods, and model systems can be connected and analyzed together.
The mechanism is a U01 cooperative agreement, which typically implies substantial involvement from NIH staff in coordinating activities, setting expectations, and ensuring the Hub aligns with program-wide goals. The notice specifies "Clinical Trial Not Allowed," so the work is focused on data infrastructure, curation, integration, and community enablement rather than running clinical intervention studies. The activity category is health, and the CFDA number is 93.121. Eligibility is limited to public and state-controlled institutions of higher education, reflecting the infrastructure-heavy, long-term stewardship role expected of the awardee. The opportunity was created February 14, 2018, with an original closing date of July 17, 2018.
Financially, the posting indicates an award ceiling of $1,900,000 and an expectation of one award, underscoring that this is a single-hub model where one lead institution is responsible for the platform and its services. Overall, the grant is aimed at ensuring continuity of FaceBase as a reliable, accessible, and evolving national resource for craniofacial data, while also broadening its scope by onboarding and harmonizing datasets from the wider research community so that FaceBase can serve as a central, integrative knowledgebase for the field.Apply for RFA DE 19 003
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: FaceBase 3: Craniofacial Development and Dysmorphology Data Management and Integration Hub (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121.
- This funding opportunity was created on Feb 14, 2018.
- Applicants must submit their applications by Jul 17, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,900,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education.
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